Tumor Suppressor Gene TP53
TP53, a gene on chromosome 17, encodes a tumor suppressor protein containing transcriptional activation, DNA binding and oligomerization domains. The encoded protein P53 responds to a variety of cellular stresses and regulates the expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair or metabolic changes. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome.
Evaluate Tumor Suppressor Ability
TP53 gene is a tumor suppressor gene that is associated with a variety of cancers.
Auxiliary Diagnosis and Prognosis
TP53 gene testing can determine the benign or malignant nature of the tumor and its prognosis.
Monitor Changes in Condition
Clinically, blood tests, imaging tests, etc. can be used to observe the development and progression of the disease and adjust the treatment plan in a timely manner.
